[1]欧阳洋,施荣.炎调方抑制肺泡上皮细胞凋亡减轻肺水肿机制假说[J].医学争鸣,2021,(01):30-34.[doi:10.13276/j.issn.1674-8913.2021.01.006]
 OUYANG Yang,SHI Rong.A hypothesis of mechanism of Yantiao Prescriptioninhibiting apoptosis of alveolar epithelial cells to reducepulmonary edema[J].,2021,(01):30-34.[doi:10.13276/j.issn.1674-8913.2021.01.006]
点击复制

炎调方抑制肺泡上皮细胞凋亡减轻肺水肿机制假说

参考文献/References:

[1] MIYASHITA T, AHMED A K, NAKANUMA S, et al. Athree-phase approach for the early identification of acutelung injury induced by severe sepsis[J]. In Vivo, 2016,30(4):341-349.
[2] 刘芬, 李勇, 彭菲菲, 等. iPSC-MSC来源的外泌体对LPS刺激肺泡巨噬细胞产生炎性因子的影响[J]. 实验与检验医学, 2016, 34(1):4-7.
[3] XU X, ZHU Q, NIU F, et al. A2BAR activation attenuatesacute lung injury by inhibiting alveolar epithelial cellapoptosis both in vivo and in vitro[J]. Am J Physiol CellPhysiol, 2018, 315(4):C558-C570.
[4] CHANG Y W, TSENG C P, LEE C H, et al. β-Nitrostyrenederivatives attenuate LPS-mediated acute lung injury viathe inhibition of neutrophil-platelet interactions and NETrelease[J]. Am J Physiol Lung Cell Mol Physiol, 2018,314(4):L654-L669.
[5] 李健, 张红. PI3K/AKT信号通路与细胞凋亡在体外循环肺损伤中的研究进展[J]. 贵州医药, 2017, 41(4):414-416.
[6] QIN S, CHEN M, JI H, et al. MiR‑21‑5p regulates type IIalveolar epithelial cell apoptosis in hyperoxic acute lunginjury[J]. Mol Med Rep, 2018, 17(4):5796-5804.
[7] 支佳琦, 王青青. 肺泡上皮细胞在肺部免疫中的作用[J].中国免疫学杂志, 2018, 34(10):1596-1601.
[8] LEE W L, SLUTSKY A S. Sepsis and endothelialpermeability[J]. N Engl J Med, 2010, 363(7):689-691.
[9] VADÁSE I, SZNAJDER J I. Gas exchange disturbancesregulate alveolar fluid clearance during acute lung injury[J].Front Immunol, 2017, 8:757.
[10] POTERA R M, CAO M, JORDAN L F, et al. Alveolarmacrophage chemokine secretion mediates neutrophiliclung injury in nox2-deficient mice[J]. Inflammation, 2019,42(1):185-198.
[11] YANG J, ZHAO Y, ZHANG P, et al. Hemorrhagic shockprimes for lung vascular endothelial cell pyroptosis: role inpulmonary inflammation following LPS[J]. Cell Death Dis,2016, 7(9):e2363.
[12] 朱召浩, 朱嘉羚, 戚薇岩, 等. 肺泡上皮细胞的研究进展[J]. 药物生物技术, 2017, 24(2):159-162.
[13] FLODBY P, KIM Y H, BEARD L L, et al. Knockout micereveal a major role for alveolar epithelial type I cells in alveolar fluid clearance[J]. Am J Respir Cell Mol Biol, 2016,55(3):395-406.
[14] MONSEL A, CALFEE C S. Focusing on the alveolarepithelium: alveolar fluid clearance in diffuse versus focalacute respiratory distress syndrome[J]. Anaesth Crit CarePain Med, 2016, 35(2):75-77.
[15] ZHANG J L, ZHUO X J, LIN J, et al. Maresin 1 stimulatesalveolar fluid clearance through the alveolar epithelialsodium channel Na,K-ATPase via the ALX/PI3K/Nedd4-2pathway[J]. Lab Invest, 2017, 97(5):543-554.
[16] NIE H, CUI Y, WU S, et al. 1, 25-dihydroxyvitamin Denhances alveolar fluid clearance by upregulating theexpression of epithelial sodium channels[J]. J Pharm Sci,2016, 105(1):333-338.
[17] DENG J, WANG D X, LIANG A L, et al. Effects of baicalinon alveolar fluid clearance and α-ENaC expression inrats with LPS-induced acute lung injury[J]. Can J PhysiolPharmacol, 2017, 95(2):122-128.
[18] LI J W, WU X. Mesenchymal stem cells ameliorate LPSinducedacute lung injury through KGF promoting alveolarfluid clearance of alveolar type II cells[J]. Eur Rev MedPharmacol Sci, 2015, 19(13):2368-2378.
[19] GWOZDZIDNSKA P, BUCHBINDER B A, MAYER K,et al. Hypercapnia impairs ENaC cell surface stabilityby promoting phosphorylation, polyubiquitination andendocytosis of β-ENaC in a human alveolar epithelial cellline[J]. Front Immunol, 2017, 8:591.
[20] HUANG C, ZHENG H, HE W, et al. Ghrelin amelioratesthe human alveolar epithelial A549 cell apoptosis inducedby lipopolysaccharide[J]. Biochem Biophys Res Commun,2016, 474(1):83-90.
[21] LEVINE S J. Fas-mediated alveolar epithelial cell apoptosisin acute lung injury: friend or foe[J]. Crit Care Med, 2002,30(7):1667-1668.
[22] 王玲, 刘辉国. 金雀异黄素对脂多糖诱导人肺泡上皮细胞A549炎症及凋亡的影响[J]. 中国中医药信息杂志,2017, 24(3):57-60.
[23] LIU W L, LIU Z W, LI T S, et al. Hydrogen sulfide donorregulates alveolar epithelial cell apoptosis in rats with acutelung injury[J]. Chin Med J (Engl), 2013, 126(3):494-499.
[24] ROZYCKI H J. Potential contribution of type I alveolarepithelial cells to chronic neonatal lung disease[J]. FrontPediatr, 2014, 2:45.
[25] JANSING N L, MCCLENDON J, HENSON P M, et al.Unbiased quantitation of alveolar type II to alveolar type Icell transdifferentiation during repair after lung injury inmice[J]. Am J Respir Cell Mol Biol, 2017, 57(5):519-526.
[26] LIAO Y, YANG F, LI X, et al. The impact of caspase-8on non-small cell lung cancer brain metastasis in II/IIIstage patient[J]. Neoplasma, 2015. Online ahead of print.DOI:10.4149/neo_2015_043.
[27] 弓娟琴. Fas介导的凋亡与caspase家族[J]. 国外医学·皮肤性病学分册, 2001, 27(5):279-281.
[28] YONESHIGE A, HAGIYAMA M, INOUE T, et al. Increasedectodomain shedding of cell adhesion molecule 1 as a causeof type II alveolar epithelial cell apoptosis in patients withidiopathic interstitial pneumonia[J]. Respir Res, 2015, 16:90.
[29] MIMAE T, HAGIYAMA M, INOUE T, et al. Increasedectodomain shedding of lung epithelial cell adhesionmolecule 1 as a cause of increased alveolar cell apoptosis inemphysema[J]. Thorax, 2014, 69(3):223-231.
[30] 李旭, 陈岩, 白雪松, 等. 中药治疗急性肺损伤/急性呼吸窘迫综合征作用机制研究进展[J]. 辽宁中医药大学学报,2017, 19(1):166-170.
[31] 施荣, 熊旭东. 通腑清营法治疗脓毒症热毒内盛证临床观察[J]. 中国中医急症, 2011, 20(4):521-522.
[32] 张涛, 熊旭东, 李淑芳. 通腑泻肺方治疗肺系脓毒症(痰热壅肺证)的临床研究[J]. 中国中医急症, 2014,23(10):1788-1790,1805.
[33] 何淼, 熊旭东, 沈晓红. 炎调方对脓毒症急性呼吸窘迫综合征(热炽营血证)患者血细胞因子的影响[J]. 中国中医急症, 2013, 22(7): 1097-1099.
[34] 沈晓红, 何淼, 熊旭东, 等. 炎调方对脓毒症大鼠肺热休克蛋白70和核因子-κB的调控作用[J]. 上海中医药大学学报, 2013, 27(3):69-72.
[35] 施荣, 熊旭东, 李淑芳, 等. 炎调方对脓毒症大鼠血清炎症因子的调控作用[J]. 中国中医急症, 2012, 21(3):397-398.

相似文献/References:

[1]简文,樊爱琳,尹文,等.山莨菪碱治疗兔创伤性急性肺损伤分子生物学机制的实验研究[J].医学争鸣,2008,(11):985.
 IAN Wen,FAN Ai Lin,YIN Wen,et al.Molecular biological mechanism of anisodamine in treatment of acute traumatic lung injury in rabbits[J].,2008,(01):985.
[2]杨溢,甘华,李正荣,等.连续性血液净化对肺泡上皮细胞Connexin43的影响[J].医学争鸣,2009,(13):1220.
 YANG Yi,GAN Hua,LI Zheng Rong,et al.Effects of continuous blood purification on Connexin43 in human alveolar epithelial cells[J].,2009,(01):1220.
[3]欧阳洋,施 荣.炎调方抑制肺泡上皮细胞凋亡减轻肺水肿机制假说[J].医学争鸣,2021,(预出版):1.
 OUYANG Yang,SHI Rong.A hypothesis of mechanism of Yantiao Prescription inhibiting apoptosis of alveolar epithelial cells to reduc e pulmonary edema[J].,2021,(01):1.

备注/Memo

基金项目:国家自然科学基金(81774057,81974539);上海市临床重点专科项目(shslczdzk04402)
通信作者:施 荣。Tel:13512143791,E-mail:doctorshi@126.com
作者简介:欧阳洋。学士,主治医师。研究方向:中西医结合治疗急危重症。Tel:13321951632,E-mail:ssdouyang@163.com

更新日期/Last Update: 2021-01-20